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04.12.2014

Organovo and Yale Announce Collaboration on 3D Bioprinting for Organ Transplantion

Without a doubt, the most exciting applications for 3D printing, reside within the medical field. Companies like San Diego-based Organovo (NYSE: ONVO) are making substantial progress within the area of 3D bioprinting, allowing for the custom fabrication of human tissue. Just last month, the company announced the commercial availability of their exVive3D human liver tissue. The primary objective of this new product is to provide tissue samples to pharmaceutical companies who can then use them for drug toxicity testing.

Organovo is not stopping their though. The company is at the forefront of the bioprinting space, and has plans to eventually begin printing human organ tissue which can be used for transplantation. At first they plan to transplant tissue onto failing organs such as the liver, with their ultimate goal being the 3D printing of entire human organs for transplant surgery.

Today, these goals have taken a step forward, as Organovo has announced a collaboration with the Yale School of Medicine, Department of Surgery to develop bioprinted tissues for surgical transplantation research. This research will be made possible, thanks in part to a non-profit medical charity called The Methuselah Foundation, who has contributed important funding for this collaboration to Yale as well as other universities.  The goal of this foundation is to find ways in which 90-year-old people can have the health profile of a 50-year-old person by the year 2030.

“Developing organs for surgical implantation will take meaningful efforts and focused partnerships. This collaboration with Yale, which combines their expertise and technology with our own, is one important step in progressing towards implantable, therapeutic tissues,” said Keith Murphy, chairman and CEO of Organovo. “We are grateful to the Methuselah Foundation for their generous gift that gives those working towards significant breakthroughs in organ bioprinting an opportunity to use the NovoGen bioprinter and enable greater access to Organovo’s powerful platform.”

Back in October, at the Inside 3D Printing Conference in Santa Clara, California, Murphy stated that his company would likely be printing partial livers for human implantation within just 4-6 years. This collaboration could play an integral part in their drive to meet this timeline.

“We are excited to begin this collaboration with Organovo and are honored to be part of Methuselah’s University 3D Bioprinter Program, which gives our key researchers access to cutting-edge 3D bioprinting technology,” said Dr. John Geibel, Vice Chairman, Director of Surgical Research, and Professor of Surgery and Cellular and Molecular Physiology at Yale University. “This collaboration is a great way to bring the best minds of both worlds to solve a major research and medical goal – using bioprinting to produce transplantable tissues.”

The work being done here could potentially lead to a drastic increase in the supply of human organs for transplantation. While most experts believe we are still 10+ years away from 3D printing entire organs for transplantation, research like this could indeed push that time frame a bit closer.

Let’s hear your thoughts on this collaboration in the Organovo & Yale 3D Bioprinting forum thread on 3DPB.com.

Source: http://3dprint.com/28404/organovo-yale-bioprinting/




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Founded by Russian entrepreneur Dmitry Itskov in February 2011 with the participation of leading Russian specialists in the field of neural interfaces, robotics, artificial organs and systems.

The main goals of the 2045 Initiative: the creation and realization of a new strategy for the development of humanity which meets global civilization challenges; the creation of optimale conditions promoting the spiritual enlightenment of humanity; and the realization of a new futuristic reality based on 5 principles: high spirituality, high culture, high ethics, high science and high technologies. 

The main science mega-project of the 2045 Initiative aims to create technologies enabling the transfer of a individual’s personality to a more advanced non-biological carrier, and extending life, including to the point of immortality. We devote particular attention to enabling the fullest possible dialogue between the world’s major spiritual traditions, science and society.

A large-scale transformation of humanity, comparable to some of the major spiritual and sci-tech revolutions in history, will require a new strategy. We believe this to be necessary to overcome existing crises, which threaten our planetary habitat and the continued existence of humanity as a species. With the 2045 Initiative, we hope to realize a new strategy for humanity's development, and in so doing, create a more productive, fulfilling, and satisfying future.

The "2045" team is working towards creating an international research center where leading scientists will be engaged in research and development in the fields of anthropomorphic robotics, living systems modeling and brain and consciousness modeling with the goal of transferring one’s individual consciousness to an artificial carrier and achieving cybernetic immortality.

An annual congress "The Global Future 2045" is organized by the Initiative to give platform for discussing mankind's evolutionary strategy based on technologies of cybernetic immortality as well as the possible impact of such technologies on global society, politics and economies of the future.

 

Future prospects of "2045" Initiative for society

2015-2020

The emergence and widespread use of affordable android "avatars" controlled by a "brain-computer" interface. Coupled with related technologies “avatars’ will give people a number of new features: ability to work in dangerous environments, perform rescue operations, travel in extreme situations etc.
Avatar components will be used in medicine for the rehabilitation of fully or partially disabled patients giving them prosthetic limbs or recover lost senses.

2020-2025

Creation of an autonomous life-support system for the human brain linked to a robot, ‘avatar’, will save people whose body is completely worn out or irreversibly damaged. Any patient with an intact brain will be able to return to a fully functioning  bodily life. Such technologies will  greatly enlarge  the possibility of hybrid bio-electronic devices, thus creating a new IT revolution and will make  all  kinds of superimpositions of electronic and biological systems possible.

2030-2035

Creation of a computer model of the brain and human consciousness  with the subsequent development of means to transfer individual consciousness  onto an artificial carrier. This development will profoundly change the world, it will not only give everyone the possibility of  cybernetic immortality but will also create a friendly artificial intelligence,  expand human capabilities  and provide opportunities for ordinary people to restore or modify their own brain multiple times.  The final result  at this stage can be a real revolution in the understanding of human nature that will completely change the human and technical prospects for humanity.

2045

This is the time when substance-independent minds will receive new bodies with capacities far exceeding those of ordinary humans. A new era for humanity will arrive!  Changes will occur in all spheres of human activity – energy generation, transportation, politics, medicine, psychology, sciences, and so on.

Today it is hard to imagine a future when bodies consisting of nanorobots  will become affordable  and capable of taking any form. It is also hard to imagine body holograms featuring controlled matter. One thing is clear however:  humanity, for the first time in its history, will make a fully managed evolutionary transition and eventually become a new species. Moreover,  prerequisites for a large-scale  expansion into outer space will be created as well.

 

Key elements of the project in the future

• International social movement
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