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Researchers build nanoscale autonomous walking machine from DNA
Researchers at The University of Texas at Austin have developed a nanoscale machine made of DNA that can randomly walk in any direction across bumpy surfaces. Future applications of such a DNA walker might include a cancer detector that could roam the human body searching for cancerous cells and tagging them for medical imaging or drug targeting.
The study by researchers Cheulhee Jung, Peter B. Allen and Andrew Ellington, published this week in the journal Nature Nanotechnology ("A stochastic DNA walker that traverses a microparticle surface"), developed DNA machines that were able to walk, unprogrammed and in different directions, over a DNA-coated surface. Previously, nanoparticle walkers were only able to walk on precise and programmed one- and two-dimensional paths. This walker was able to move 36 steps, and its movement in a random fashion is different from movement seen in other studies.
The study by researchers Cheulhee Jung, Peter B. Allen and Andrew Ellington, published this week in the journal Nature Nanotechnology ("A stochastic DNA walker that traverses a microparticle surface"), developed DNA machines that were able to walk, unprogrammed and in different directions, over a DNA-coated surface. Previously, nanoparticle walkers were only able to walk on precise and programmed one- and two-dimensional paths. This walker was able to move 36 steps, and its movement in a random fashion is different from movement seen in other studies.
There also may be implications for future delivery of nanoscale therapeutics."This is an important step forward in developing nanoscale nucleic acid machines that can autonomously act under a variety of conditions, including in the body," said Ellington, professor in the Department of Molecular Biosciences and member of the UT Center for Systems and Synthetic Biology. "DNA nanotechnology is especially interesting because it explores the world of 'matter computers,' where computations (including walking) are carried out by physical objects, rather than by electronic or magnetic shuttles. DNA walkers may eventually allow protective cells to walk the surface of organs, constantly computing whether a cancer is present."
Although it may be a long march from diagnosing cancer to curing it, "All breakthroughs begin with baby steps. Only in this case, they are the steps of a DNA walker," said co-author Jung. More immediate practical applications may include deploying the DNA walker in the body so that it can amplify signals from cancer cells to make them more easily identified and targeted by doctors.
The walker is made from a single piece of DNA with two legs connected by a torso. Like a human, it moves by putting one leg forward, then lifting the other leg and putting it forward. The walker autonomously and randomly decides where to put its leg on each step. The study demonstrated that as the nanoscale machine walked, it did not go over the same area twice.
Source: http://www.nanowerk.com/nanotechnology-news/newsid=41746.php
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Founded by Russian entrepreneur Dmitry Itskov in February 2011 with the participation of leading Russian specialists in the field of neural interfaces, robotics, artificial organs and systems.
The main goals of the 2045 Initiative: the creation and realization of a new strategy for the development of humanity which meets global civilization challenges; the creation of optimale conditions promoting the spiritual enlightenment of humanity; and the realization of a new futuristic reality based on 5 principles: high spirituality, high culture, high ethics, high science and high technologies.
The main science mega-project of the 2045 Initiative aims to create technologies enabling the transfer of a individual’s personality to a more advanced non-biological carrier, and extending life, including to the point of immortality. We devote particular attention to enabling the fullest possible dialogue between the world’s major spiritual traditions, science and society.
A large-scale transformation of humanity, comparable to some of the major spiritual and sci-tech revolutions in history, will require a new strategy. We believe this to be necessary to overcome existing crises, which threaten our planetary habitat and the continued existence of humanity as a species. With the 2045 Initiative, we hope to realize a new strategy for humanity's development, and in so doing, create a more productive, fulfilling, and satisfying future.
The "2045" team is working towards creating an international research center where leading scientists will be engaged in research and development in the fields of anthropomorphic robotics, living systems modeling and brain and consciousness modeling with the goal of transferring one’s individual consciousness to an artificial carrier and achieving cybernetic immortality.
An annual congress "The Global Future 2045" is organized by the Initiative to give platform for discussing mankind's evolutionary strategy based on technologies of cybernetic immortality as well as the possible impact of such technologies on global society, politics and economies of the future.
Future prospects of "2045" Initiative for society
2015-2020
The emergence and widespread use of affordable android "avatars" controlled by a "brain-computer" interface. Coupled with related technologies “avatars’ will give people a number of new features: ability to work in dangerous environments, perform rescue operations, travel in extreme situations etc.
Avatar components will be used in medicine for the rehabilitation of fully or partially disabled patients giving them prosthetic limbs or recover lost senses.
2020-2025
Creation of an autonomous life-support system for the human brain linked to a robot, ‘avatar’, will save people whose body is completely worn out or irreversibly damaged. Any patient with an intact brain will be able to return to a fully functioning bodily life. Such technologies will greatly enlarge the possibility of hybrid bio-electronic devices, thus creating a new IT revolution and will make all kinds of superimpositions of electronic and biological systems possible.
2030-2035
Creation of a computer model of the brain and human consciousness with the subsequent development of means to transfer individual consciousness onto an artificial carrier. This development will profoundly change the world, it will not only give everyone the possibility of cybernetic immortality but will also create a friendly artificial intelligence, expand human capabilities and provide opportunities for ordinary people to restore or modify their own brain multiple times. The final result at this stage can be a real revolution in the understanding of human nature that will completely change the human and technical prospects for humanity.
2045
This is the time when substance-independent minds will receive new bodies with capacities far exceeding those of ordinary humans. A new era for humanity will arrive! Changes will occur in all spheres of human activity – energy generation, transportation, politics, medicine, psychology, sciences, and so on.
Today it is hard to imagine a future when bodies consisting of nanorobots will become affordable and capable of taking any form. It is also hard to imagine body holograms featuring controlled matter. One thing is clear however: humanity, for the first time in its history, will make a fully managed evolutionary transition and eventually become a new species. Moreover, prerequisites for a large-scale expansion into outer space will be created as well.
Key elements of the project in the future
• International social movement
• social network immortal.me
• charitable foundation "Global Future 2045" (Foundation 2045)
• scientific research centre "Immortality"
• business incubator
• University of "Immortality"
• annual award for contribution to the realization of the project of "Immortality”.