/ News
Russian 3D-bioprinted thyroid gland implant proves functional in mice
A Moscow laboratory has conducted the first successful organ translation using a unique Russian 3D-printing technology. The breakthrough could potentially help millions suffering from thyroid disorders – and paves the way for printing other human organs.
The thyroid, a butterfly-shaped gland in the neck, can have a dramatic impact on a huge variety of human bodily functions. The groundbreaking operation, thus far only in rodents, was performed by a team from the 3D Bioprinting Solutions Laboratory in the Russian capital some three months ago.
“Then we were monitoring them over eight weeks and the level of the hormone continued growing," said Elena Bulanova, 3D Bioprinting Solutions Laboratory Head.
The thyroid glands in mice were first killed by a radioactive iodine injection, before the research team transplanted newly-printed organs into their subjects.
Three weeks into the experiment, the team, headed by Vladimir Mironov, observed “higher” levels of the hormone T4, which is responsible for growth and the metabolism, and measured higher body temperatures, Bulanova said.
After 11 weeks of monitoring the subjects’ 3D printed thyroid glands, they were fully functional with completely restored thyroid function.
“All in all we consider experiment to be successfully conducted because we managed to raise the level of hormone T4,” Bulanova said.
The 3D-printed organ consists of several types of tissues, and features blood vessels to substitute the thyroid gland of a living organism. The lab’s undertaking to transplant the thyroid first began in March 2015, when the organ was first printed using the Russian bio printer FABION.
In further experiments and in printing other organs, potentially human, researchers are planning to use undifferentiated stem cells taken from an adult organism, which are very similar to embryonary cells.
“There are many new and interesting but complicated tasks which need to be completed, but it is another level of the development of the industry,” said 3D Bioprinting Solutions Executive Director Youssef Hesuani.
The breakthrough of 3D Bioprinting Solutions Laboratory was presented at a scientific conference in the Netherlands earlier this month. During the presentation the head of research, Vladimir Mironov told the scientific community that their 3D-printed organ is able to restore thyroid function in mice suffering from hypothyroidism — a condition where thyroid gland doesn’t produce enough hormones.
Scientists hope that the new breakthrough will one day help millions of people with different thyroid disorders, as the thyroid gland influences almost all of the metabolic processes in human body.
Source: https://www.rt.com/news/323494-russian-3d-printed-thyroid/
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Founded by Russian entrepreneur Dmitry Itskov in February 2011 with the participation of leading Russian specialists in the field of neural interfaces, robotics, artificial organs and systems.
The main goals of the 2045 Initiative: the creation and realization of a new strategy for the development of humanity which meets global civilization challenges; the creation of optimale conditions promoting the spiritual enlightenment of humanity; and the realization of a new futuristic reality based on 5 principles: high spirituality, high culture, high ethics, high science and high technologies.
The main science mega-project of the 2045 Initiative aims to create technologies enabling the transfer of a individual’s personality to a more advanced non-biological carrier, and extending life, including to the point of immortality. We devote particular attention to enabling the fullest possible dialogue between the world’s major spiritual traditions, science and society.
A large-scale transformation of humanity, comparable to some of the major spiritual and sci-tech revolutions in history, will require a new strategy. We believe this to be necessary to overcome existing crises, which threaten our planetary habitat and the continued existence of humanity as a species. With the 2045 Initiative, we hope to realize a new strategy for humanity's development, and in so doing, create a more productive, fulfilling, and satisfying future.
The "2045" team is working towards creating an international research center where leading scientists will be engaged in research and development in the fields of anthropomorphic robotics, living systems modeling and brain and consciousness modeling with the goal of transferring one’s individual consciousness to an artificial carrier and achieving cybernetic immortality.
An annual congress "The Global Future 2045" is organized by the Initiative to give platform for discussing mankind's evolutionary strategy based on technologies of cybernetic immortality as well as the possible impact of such technologies on global society, politics and economies of the future.
Future prospects of "2045" Initiative for society
2015-2020
The emergence and widespread use of affordable android "avatars" controlled by a "brain-computer" interface. Coupled with related technologies “avatars’ will give people a number of new features: ability to work in dangerous environments, perform rescue operations, travel in extreme situations etc.
Avatar components will be used in medicine for the rehabilitation of fully or partially disabled patients giving them prosthetic limbs or recover lost senses.
2020-2025
Creation of an autonomous life-support system for the human brain linked to a robot, ‘avatar’, will save people whose body is completely worn out or irreversibly damaged. Any patient with an intact brain will be able to return to a fully functioning bodily life. Such technologies will greatly enlarge the possibility of hybrid bio-electronic devices, thus creating a new IT revolution and will make all kinds of superimpositions of electronic and biological systems possible.
2030-2035
Creation of a computer model of the brain and human consciousness with the subsequent development of means to transfer individual consciousness onto an artificial carrier. This development will profoundly change the world, it will not only give everyone the possibility of cybernetic immortality but will also create a friendly artificial intelligence, expand human capabilities and provide opportunities for ordinary people to restore or modify their own brain multiple times. The final result at this stage can be a real revolution in the understanding of human nature that will completely change the human and technical prospects for humanity.
2045
This is the time when substance-independent minds will receive new bodies with capacities far exceeding those of ordinary humans. A new era for humanity will arrive! Changes will occur in all spheres of human activity – energy generation, transportation, politics, medicine, psychology, sciences, and so on.
Today it is hard to imagine a future when bodies consisting of nanorobots will become affordable and capable of taking any form. It is also hard to imagine body holograms featuring controlled matter. One thing is clear however: humanity, for the first time in its history, will make a fully managed evolutionary transition and eventually become a new species. Moreover, prerequisites for a large-scale expansion into outer space will be created as well.
Key elements of the project in the future
• International social movement
• social network immortal.me
• charitable foundation "Global Future 2045" (Foundation 2045)
• scientific research centre "Immortality"
• business incubator
• University of "Immortality"
• annual award for contribution to the realization of the project of "Immortality”.
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